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When administered orally, the vast majority of opiate absorption occurs inside the compact intestine. When massive doses of opiates are consumed, this can cause gastric aperistalsis in addition to a hold off in gastric emptying and absorption from the drug. Once in the body, opiates are broken down because of the liver to inactive compounds which c
The identical enzyme is liable also to the degradation of AEA, which in most of the cited capabilities of OEA could be noticed for a practical antagonist. This is especially apparent for that modulation of food ingestion and lipid metabolism, for which AEA and OEA Participate in two opposite roles: AEA stimulates appetite and promotes lipogenesis a